Programming DNA tube circumferences.

نویسندگان

  • Peng Yin
  • Rizal F Hariadi
  • Sudheer Sahu
  • Harry M T Choi
  • Sung Ha Park
  • Thomas H Labean
  • John H Reif
چکیده

Synthesizing molecular tubes with monodisperse, programmable circumferences is an important goal shared by nanotechnology, materials science, and supermolecular chemistry. We program molecular tube circumferences by specifying the complementarity relationships between modular domains in a 42-base single-stranded DNA motif. Single-step annealing results in the self-assembly of long tubes displaying monodisperse circumferences of 4, 5, 6, 7, 8, 10, or 20 DNA helices.

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عنوان ژورنال:
  • Science

دوره 321 5890  شماره 

صفحات  -

تاریخ انتشار 2008